Anticorps Polyclonal de lapin anti-RTTN

RTTN Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31232-1-PBS

Synonymes

Rotatin, MSSP

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Galerie de données de validation

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  WB analysis using 31232-1-AP (same clone as 31232-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31232-1-AP (RTTN antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31232-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31232-1-PBS cible RTTN dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RTTN Protéine recombinante Ag34960
• Nom complet: rotatin
• Masse moléculaire calculée: 249 kDa
• Poids moléculaire observé: 246 kDa
• Numéro d’acquisition GenBank: NM_173630
• Symbole du gène: RTTN
• Identification du gène (NCBI): 25914
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RTTN, also known as Rotatin, is an evolutionarily conserved protein that is associated with the centrosome and plays a crucial role in centriole biogenesis. It is found in many organisms and was initially identified in a mutant mouse that exhibited defects in axial rotation and left-right specification. RTTN is required for proper mitotic progression, the maintenance of spindle pole integrity, and correct spindle positioning. Loss of RTTN can lead to mitotic defects, including G2/M phase arrest and increased aneuploidy cells.

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