Anticorps Polyclonal de lapin anti-RUNX3

RUNX3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27099-1-PBS

Synonymes

AML2, CBF alpha 3, CBFA3, CBF-alpha-3, Core-binding factor subunit alpha-3

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Galerie de données de validation

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  WB analysis using 27099-1-AP (same clone as 27099-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 27099-1-AP (RUNX3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27099-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27099-1-PBS cible RUNX3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: RUNX3 Protéine recombinante Ag24339
• Nom complet: runt-related transcription factor 3
• Masse moléculaire calculée: 44 kDa
• Poids moléculaire observé: 45-55 kDa
• Numéro d’acquisition GenBank: BC013362
• Symbole du gène: RUNX3
• Identification du gène (NCBI): 864
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

RUNX3, also known as AML2, CBFA3 and PEBP2A3, is a member of the RUNX family of transcription factors, which are crucial regulators of embryonic development and play key roles in various biological processes such as cell proliferation, apoptosis, differentiation and lineage commitment (PMID: 38430423). This protein functions as a tumour suppressor and is frequently deleted or transcriptionally silenced in various cancers, including gastric and colon cancer.

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