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Anticorps Polyclonal de lapin anti-S1PR1/EDG1

S1PR1/EDG1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29318-1-PBS

Synonymes

S1PR1, EDG1, EDG 1, ECGF1, D1S3362

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using S1PR1/EDG1 Polyclonal antibody (29318-1-AP)

    WB analysis using 29318-1-AP (same clone as 29318-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 29318-1-AP (S1PR1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29318-1-PBS in a different storage buffer formulation.

Informations sur le produit

29318-1-PBS cible S1PR1/EDG1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène S1PR1/EDG1 Protéine recombinante Ag28083
Nom complet sphingosine-1-phosphate receptor 1
Masse moléculaire calculée 43 kDa
Poids moléculaire observé45-50 kDa
Numéro d’acquisition GenBankBC018650
Symbole du gène S1PR1
Identification du gène (NCBI) 1901
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

S1PR1 (sphingosine-1-phosphate receptor 1), also known as S1P1 or EDG1, is one of five G-protein-coupled receptors for sphingosine-1-phosphate (S1P) (PMID: 18787560). S1P1 and its receptors have important regulatory functions in normal physiology and disease processes, particularly involving the immune, central nervous, and cardiovascular systems (PMID: 21339489). S1PR1 is widely expressed in various cell types, including endothelial cells and lymphocytes (PMID: 14737169). S1P-S1PR1 plays a major role in lymphocyte egress and chemotaxis, cell proliferation and survival, and tumor angiogenesis and metastasis (PMID: 21102457).

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