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Anticorps Monoclonal anti-SALL4

SALL4 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2B5B2

N° de cat : 66236-1-PBS

Synonymes

2B5B2, DRRS, HSAL4, Sal like protein 4, Sal-like protein 4

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of K-562 cells using SALL4 Monoclonal antibody (66236-1-Ig)

    WB analysis of K-562 using 66236-1-Ig (same clone as 66236-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 66236-1-Ig (SALL4 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66236-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of K-562 cells using SALL4 Monoclonal antibody (66236-1-Ig)

    WB analysis of K-562 using 66236-1-Ig (same clone as 66236-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 66236-1-Ig (SALL4 Antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66236-1-PBS in a different storage buffer formulation.

Informations sur le produit

66236-1-PBS cible SALL4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène SALL4 Protéine recombinante Ag17480
Nom complet sal-like 4 (Drosophila)
Masse moléculaire calculée 1053 aa, 112 kDa
Poids moléculaire observé 165 kDa
Numéro d’acquisition GenBankBC111714
Symbole du gène SALL4
Identification du gène (NCBI) 57167
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SALL4, also named as Sal-like protein 4 or Zinc finger protein 797, Contains 7 C2H2-type zinc fingers and belongs to the sal C2H2-type zinc-finger protein family. SALL4 is constitutively expressed in acute myeloid leukemia. The constitutive expression of SALL4in mice is sufficient to induce MDS-like symptoms and transformation to AML that is transplantable. SALL4 is able to bind beta-catenin and activate the Wnt/beta-catenin signaling pathway. Sequence analysis of the larger cDNA fragment isolated revealed a single, large open-reading frame, designated as SALL4A, that started from a strong consensus initiation sequence and was expected to encode 1053 amino acids. The other splicing variant of SALL4, designated SALL4B, lacked the region corresponding to amino acids 385 to 820 of the full-length SALL4A. The putative protein encoded by SALL4B cDNA was expected to consist of 617 amino acids.

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