Anticorps Recombinant de lapin anti-SAMD9L

SAMD9L Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241250A2

N° de cat : 84109-1-PBS

Synonymes

241250A2, C7orf6, DRIF2, KIAA2005, SAM domain-containing protein 9-like

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Galerie de données de validation

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  WB analysis using 84109-1-RR (same clone as 84109-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84109-1-RR (SAMD9L antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84109-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84109-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84109-1-RR against Human SAMD9L were performed. The affinity constant is 1.14 nM.

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Informations sur le produit

84109-1-PBS cible SAMD9L dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: SAMD9L Protéine recombinante Ag18541
• Nom complet: sterile alpha motif domain containing 9-like
• Masse moléculaire calculée: 1584 aa, 185 kDa
• Poids moléculaire observé: 160-180 kDa
• Numéro d’acquisition GenBank: BC127118
• Symbole du gène: SAMD9L
• Identification du gène (NCBI): 219285
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Sterile alpha motif domain-containing protein 9-like(SAMD9L), also named C7orf6, DRIF2, KIAA2005, and UEF, is a cytoplasmic protein that acts as a tumor suppressor but also plays a key role in cell proliferation and the innate immune response to viral infection. SAMD9L protein is an endosome fusion facilitator that causes myeloid malignancies in mice similar to human diseases with monosomy 7. The SAMD9L protein also appears to play an important role in the brain, particularly the part of the brain that coordinates movement (the cerebellum). SAMD9L has two isoforms with MW 185 kDa and 47 kDa.

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