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Anticorps Polyclonal de lapin anti-SCARF1

SCARF1 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 28174-1-PBS

Synonymes

Acetyl LDL receptor, KIAA0149, Scavenger receptor class F member 1, Scavenger receptor expressed by endothelial cells 1, SREC

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using SCARF1 Polyclonal antibody (28174-1-AP)

    WB analysis using 28174-1-AP (same clone as 28174-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28174-1-AP (SCARF1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28174-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using SCARF1 Polyclonal antibody (28174-1-AP)

    IF Staining of HepG2 using 28174-1-AP (same clone as 28174-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using SCARF1 antibody (28174-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 28174-1-PBS in a different storage buffer formulation.

Informations sur le produit

28174-1-PBS cible SCARF1 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène SCARF1 Protéine recombinante Ag28079
Nom complet scavenger receptor class F, member 1
Masse moléculaire calculée 830 aa, 87 kDa
Poids moléculaire observé90 kDa, 180 kDa
Numéro d’acquisition GenBankBC039735
Symbole du gène SCARF1
Identification du gène (NCBI) 8578
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Scavenger receptor class F member 1 (SCARF1), also known as scavenger receptor expressed by endothelial cells (SREC)-I, belongs to the scavenger receptor (SR) superfamily. SCARF1 has been shown to bind modified low density lipoproteins (LDLs), including acetylated (Ac-) and oxidized (ox-) LDLs (PMID: 29725698; PMID: 15145948). In addition to binding and internalizing a diverse range of endogenous proteins, SCARF1 also binds a wide array of viral, fungal, and bacterial antigens (PMID: 29242513). SCARF1 has a calculated molecular weight of 87 kDa, with a molecular weight of 140-160 kDa due to N-glycosylation (PMID: 22279061; PMID: 15145948). SCARF1 can also exist as a dimer (~ 180 kDa) and a truncated soluble form (~ 60 kDa) (PMID: 29242513; PMID: 29725698).

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