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Anticorps Recombinant de lapin anti-SCN11A

SCN11A Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250003E1

N° de cat : 85740-1-PBS

Synonymes

hNaN, NaN, NAV1.9, PN5, SCN12A

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using SCN11A Recombinant antibody (85740-1-RR)

    WB analysis using 85740-1-RR (same clone as 85740-1-PBS)

    rat brain tissue were subjected to SDS PAGE followed by western blot with 85740-1-RR (SCN11A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85740-1-PBS in a different storage buffer formulation.

Informations sur le produit

85740-1-PBS cible SCN11A dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

Réactivité Humain, rat
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Peptide
Nom complet sodium channel, voltage-gated, type XI, alpha subunit
Masse moléculaire calculée 205 kDa
Poids moléculaire observé205 kDa
Numéro d’acquisition GenBankNM_001349253
Symbole du gène SCN11A
Identification du gène (NCBI) 11280
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Sodium channel protein type 11 subunit alpha (SCN11A, also known as Nav1.9) is crucial for generating action potentials and regulating neuronal excitability, particularly in nociceptive neurons of the dorsal root ganglia (DRG) and trigeminal ganglia (PMID: 33752606). Nav1.9 channels are involved in the formation of pain-sensing and have been implicated in peripheral inflammatory pain hypersensitivity. Additionally, SCN11A-mediated channels play a role in regulating colonic motility and neurotransmitter release in the enteric nervous system (PMID: 35711274).

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