Anticorps Polyclonal de lapin anti-SCN2A

SCN2A Polyclonal Antibody for WB, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27551-1-PBS

Synonymes

BFIC3, HBA, HBSC II, HBSCI, HBSCII

---

Galerie de données de validation

• 

  WB analysis using 27551-1-AP (same clone as 27551-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27551-1-AP (SCN2A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27551-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 27551-1-AP (same clone as 27551-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27551-1-AP (SCN2A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27551-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse brain using 27551-1-AP (same clone as 27551-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using SCN2A antibody (27551-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27551-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

27551-1-PBS cible SCN2A dans les applications de WB, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SCN2A Protéine recombinante Ag26022
• Nom complet: sodium channel, voltage-gated, type II, alpha subunit
• Masse moléculaire calculée: 228 kDa
• Poids moléculaire observé: ~250 kDa
• Numéro d’acquisition GenBank: NM_001040142
• Symbole du gène: SCN2A
• Identification du gène (NCBI): 6326
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The Sodium Channel, Voltage-Gated, Type II, Alpha (SCN2A) gene encodes the neuronal sodium channel NaV1.2. There are two major developmentally regulated splice isoforms of NaV1.2 that use mutually exclusive copies of the fifth coding exon and differ by one amino acid at position 209: Asparagine (Asn/N) vs. Aspartic acid (Asp/D). NaV1.2 is one of several sodium channels involved in initiation and propagation of action potentials in neurons. It's widely expressed throughout the human central nervous system, but not in peripheral tissues. (PMID: 29691040)

{{ptg:RelatedPrimaryAntibodies}}