Anticorps Polyclonal de lapin anti-SCN3B

SCN3B Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25907-1-PBS

Synonymes

HSA243396, KIAA1158, SCNB3, Sodium channel regulatory subunit beta-3, Sodium channel subunit beta 3

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Galerie de données de validation

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  WB analysis using 25907-1-AP (same clone as 25907-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 25907-1-AP (SCN3B antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25907-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25907-1-PBS cible SCN3B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SCN3B Protéine recombinante Ag23201
• Nom complet: sodium channel, voltage-gated, type III, beta
• Poids moléculaire observé: 45-50 kDa
• Numéro d’acquisition GenBank: BC126265
• Symbole du gène: SCN3B
• Identification du gène (NCBI): 55800
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The sodium channel is a multi-subunit protein complex composed of a single large α-subunit along with smaller additional β-subunits. There are at least three different β-subunit genes, SCN1b, SCN2b, and SCN3b, all of which are expressed widely in excitable tissues. The bands on Western blots for SCN3b (45-50 kDa) were significantly larger than the predicted molecular weight, which is consistent with the protein being glycosylated. The two bands on the Western blot could be due to different levels of glycosylation or alternative spliced isoforms. (PMID: 11744748)

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