Anticorps Recombinant de lapin anti-SCN3B

SCN3B Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

230316F8

N° de cat : 82959-1-PBS

Synonymes

Sodium channel subunit beta 3, Sodium channel regulatory subunit beta-3, SCNB3, KIAA1158, HSA243396

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Galerie de données de validation

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  WB analysis using 82959-1-RR (same clone as 82959-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 82959-1-RR (SCN3B antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82959-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 82959-1-PBS

  Biolayer interferometry (BLl) kinetic assays of 82959-1-RR against Human SCN3B were performed. The affinity constant is 0.429 nM.

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Informations sur le produit

82959-1-PBS cible SCN3B dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: SCN3B Protéine recombinante Ag23201
• Nom complet: sodium channel, voltage-gated, type III, beta
• Poids moléculaire observé: 29 kDa
• Numéro d’acquisition GenBank: BC126265
• Symbole du gène: SCN3B
• Identification du gène (NCBI): 55800
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The sodium voltage-gated channel beta subunit 3 (SCN3B) plays a crucial role in electrically excitable cells and conduction tissue in the heart. Some previous studies have established that genetic modification in sodium voltage-channel genes encoding for the cardiac β-subunits, such as SCN1B, SCN2B, SCN3B and SCN4B, can result in atrial fibrillation (AF). (PMID: 36362949)

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