Anticorps Monoclonal anti-SCP3

SCP3 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1A11F1

N° de cat : 66409-1-PBS

Synonymes

SYCP3, 1A11F1, COR1, SCP 3, SCP-3

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Galerie de données de validation

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  WB analysis of human testis using 66409-1-Ig (same clone as 66409-1-PBS)

  human testis tissue were subjected to SDS PAGE followed by western blot with 66409-1-Ig (SYCP3 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66409-1-PBS in a different storage buffer formulation.

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  WB analysis of DU 145 using 66409-1-Ig (same clone as 66409-1-PBS)

  DU 145 cells were subjected to SDS PAGE followed by western blot with 66409-1-Ig (SYCP3 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66409-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66409-1-PBS cible SCP3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SCP3 Protéine recombinante Ag19330
• Nom complet: synaptonemal complex protein 3
• Masse moléculaire calculée: 236 aa, 28 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC062662
• Symbole du gène: SYCP3
• Identification du gène (NCBI): 50511
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SYCP3 is an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. SYCP3 is required for centromere pairing during meiosis in male germ cells. SYCP3 is also required for normal meiosis during spermatogenesis and male fertility. Mutations in SYCP3 are associated with azoospermia in males and susceptibility to pregnancy loss in females.

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