Anticorps Polyclonal de lapin anti-SDCCAG1

• Phare
• Validé par KD/KO

SDCCAG1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11840-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 11840-1-AP (same clone as 11840-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 11840-1-AP (SDCCAG1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11840-1-PBS in a different storage buffer formulation.

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  IP experiment of A549 using 11840-1-AP (same clone as 11840-1-PBS)

  IP result of anti-SDCCAG1 (IP:11840-1-AP, 4ug; Detection:11840-1-AP 1:500) with A549 cells lysate 1800ug. This data was developed using the same antibody clone with 11840-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 11840-1-AP (same clone as 11840-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11840-1-AP (SDCCAG1 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11840-1-PBS in a different storage buffer formulation.

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  IHC staining of human lung cancer using 11840-1-AP (same clone as 11840-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11840-1-AP (SDCCAG1 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11840-1-PBS in a different storage buffer formulation.

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Informations sur le produit

11840-1-PBS cible SDCCAG1 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SDCCAG1 Protéine recombinante Ag2467
• Nom complet: serologically defined colon cancer antigen 1
• Masse moléculaire calculée: 1076 aa, 123 kDa
• Poids moléculaire observé: 130-140 kDa
• Numéro d’acquisition GenBank: BC020794
• Symbole du gène: SDCCAG1
• Identification du gène (NCBI): 9147
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SDCCAG1, also named as NEMF, is a nuclear export mediator. It can be bound to translocon-engaged 60S subunits on native ER membranes. Human SDCCAG1 has been implicated in lung cancers and it may function as a tumor suppressor gene. SDCCAG1 inactivation contributes to the transformed state of human lung cancer cells (PMID:16103875, 10575219). NEMF is also regarded as a potential biomarker for the detection of active and latent TB infections (PMID: 26818387).

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