Anticorps Monoclonal anti-SDCCAG1

SDCCAG1 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3C8A1

N° de cat : 68708-1-PBS

Synonymes

Ribosome quality control complex subunit NEMF, NY CO 1, Nuclear export mediator factor, NEMF, Homo sapiens (Human)

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Galerie de données de validation

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  WB analysis using 68708-1-Ig (same clone as 68708-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68708-1-Ig (SDCCAG1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68708-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68708-1-PBS cible SDCCAG1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SDCCAG1 Protéine recombinante Ag2467
• Nom complet: serologically defined colon cancer antigen 1
• Masse moléculaire calculée: 1076 aa, 123 kDa
• Poids moléculaire observé: 130-140 kDa
• Numéro d’acquisition GenBank: BC020794
• Symbole du gène: SDCCAG1
• Identification du gène (NCBI): 9147
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SDCCAG1, also named as NEMF, is a nuclear export mediator. It can be bound to translocon-engaged 60S subunits on native ER membranes. Human SDCCAG1 has been implicated in lung cancers and it may function as a tumor suppressor gene. SDCCAG1 inactivation contributes to the transformed state of human lung cancer cells (PMID:16103875, 10575219). NEMF is also regarded as a potential biomarker for the detection of active and latent TB infections (PMID: 26818387).

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