Anticorps Polyclonal de lapin anti-SDHC

SDHC Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14575-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 14575-1-AP (same clone as 14575-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14575-1-AP (SDHC antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14575-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 14575-1-AP (same clone as 14575-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14575-1-AP (SDHC antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14575-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 14575-1-AP (same clone as 14575-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer using 14575-1-AP (SDHC antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 14575-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 14575-1-AP (same clone as 14575-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer using 14575-1-AP (SDHC antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 14575-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14575-1-PBS cible SDHC dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SDHC Protéine recombinante Ag5775
• Nom complet: succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
• Masse moléculaire calculée: 19 kDa
• Poids moléculaire observé: 15 kDa
• Numéro d’acquisition GenBank: BC033626
• Symbole du gène: SDHC
• Identification du gène (NCBI): 6391
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SDHC(Succinate dehydrogenase cytochrome b560 subunit, mitochondrial) is also named as CYB560, SDH3 and belongs to the cytochrome b560 family. It is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Defects in SDHC are the cause of paragangliomas type 3 (PGL3) and paraganglioma and gastric stromal sarcoma (PGGSS). It has a transit peptide of 29 amino acid and has 5 isoforms produced by alternative splicing.

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