Anticorps Polyclonal de lapin anti-SDS

SDS Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 16594-1-PBS

Synonymes

EC:4.3.1.17, EC:4.3.1.19, L serine deaminase, L threonine dehydratase, L-serine deaminase

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Galerie de données de validation

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  WB analysis using 16594-1-AP (same clone as 16594-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16594-1-AP (SDS antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16594-1-PBS in a different storage buffer formulation.

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  WB analysis using 16594-1-AP (same clone as 16594-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 16594-1-AP (SDS antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16594-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 16594-1-AP (same clone as 16594-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 16594-1-AP (SDS antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16594-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 16594-1-AP (same clone as 16594-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 16594-1-AP (SDS antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 16594-1-PBS in a different storage buffer formulation.

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Informations sur le produit

16594-1-PBS cible SDS dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SDS Protéine recombinante Ag9704
• Nom complet: serine dehydratase
• Masse moléculaire calculée: 218 aa, 23 kDa
• Poids moléculaire observé: 35 kDa; 70 kDa
• Numéro d’acquisition GenBank: BC020750
• Symbole du gène: SDS
• Identification du gène (NCBI): 10993
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

L-Serine dehydratase (SDS ; SDH) catalyzes the pyridoxal phosphate (PLP) dependent deamination of l-serine to yield pyruvate. In mammals, SDH is found predominantly in the liver. Extensive studies have been carried out on SDH from rat and the enzyme has been found to play an important role in gluconeogenesis; its activity is induced by the consumption of high-protein diets, starvation and other treatments. The enzyme exists as a dimer of identical subunits, with each subunit exhibiting a bilobal architecture. (PMID: 25380533, PMID: 21878319, PMID: 14646100)

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