Anticorps Polyclonal de lapin anti-SEC61 Alpha

SEC61 Alpha Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24935-1-PBS

Synonymes

SEC61A2, Sec61 alpha-2, Protein transport protein Sec61 subunit alpha isoform 2

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Galerie de données de validation

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  WB analysis of mouse brain using 24935-1-AP (same clone as 24935-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 24935-1-AP (SEC61alpha antibody at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24935-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse liver using 24935-1-AP (same clone as 24935-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 24935-1-AP (SEC61alpha antibody at dilution of 1:600 incubated at 4 degree celsius over night. This data was developed using the same antibody clone with 24935-1-PBS in a different storage buffer formulation.

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  WB analysis of U2OS using 24935-1-AP (same clone as 24935-1-PBS)

  U2OS cells were subjected to SDS PAGE followed by western blot with 24935-1-AP (SEC61 Alpha antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24935-1-PBS in a different storage buffer formulation.

• 

  WB analysis of HEK-293 using 24935-1-AP (same clone as 24935-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 24935-1-AP (SEC61alpha antibody at dilution of 1:600 incubated at 4 degree celsius over night. This data was developed using the same antibody clone with 24935-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24935-1-PBS cible SEC61 Alpha dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SEC61 Alpha Protéine recombinante Ag20779
• Nom complet: Sec61 alpha 2 subunit (S. cerevisiae)
• Masse moléculaire calculée: 52 kDa
• Poids moléculaire observé: 52 kDa
• Numéro d’acquisition GenBank: BC026179
• Symbole du gène: SEC61 Alpha
• Identification du gène (NCBI): 55176
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The SEC61 complex is a major component of the endoplasmic reticulum (ER) translocation site (PMID: 7720858). This complex is composed of three subunits: SEC61alpha, SEC61beta and SEC61gamma. SEC61alpha is a polytopic integral membrane protein. It is a core component of the ER translocation complex, playing a crucial role in the insertion of secretory and membrane polypeptides into the ER (PMID: 9512475).

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