Anticorps Polyclonal de lapin anti-SELENBP1

SELENBP1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27449-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 27449-1-AP (same clone as 27449-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27449-1-AP (SELENBP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 27449-1-AP (same clone as 27449-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse liver using 27449-1-AP (same clone as 27449-1-PBS)

  mouse liver tissue were subjected to SDS PAGE followed by western blot with 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 27449-1-AP (same clone as 27449-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 27449-1-AP (same clone as 27449-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

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  IHC staining of rat liver using 27449-1-AP (same clone as 27449-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat liver using 27449-1-AP (same clone as 27449-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 27449-1-AP (SELENBP1 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon using 27449-1-AP (same clone as 27449-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 27449-1-AP (SELENBP1 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27449-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27449-1-PBS cible SELENBP1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SELENBP1 Protéine recombinante Ag24453
• Nom complet: selenium binding protein 1
• Masse moléculaire calculée: 52 kDa
• Poids moléculaire observé: 56 kDa
• Numéro d’acquisition GenBank: BC009084
• Symbole du gène: SELENBP1
• Identification du gène (NCBI): 8991
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SELENBP1 (selenium binding protein 1,SBP1), also known as LPSB or SP56, is a 472 amino acid peripheral membrane protein that binds selenium covalently. Selenium, an essential trace element, has been shown to have an anti-cancer effect. Many reports have described a relationship between insufficient selenium intake and increased risk of cancer. Moreover, the expression of SELENBP1 has been shown to be decreased in several tumors including cancers of the prostate, lungs, colon, and ovary (PMID: 21143902, 20332323, 18272210). SELENBP1 has four isoforms with the molecular mass of 56kD, 52kD and 45kD.

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