Anticorps Polyclonal de lapin anti-SEMA6B

SEMA6B Polyclonal Antibody for WB, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22571-1-PBS

Synonymes

SEM SEMA Y, SEMA VIB, Sema Z, SEMAN, Semaphorin 6B

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Galerie de données de validation

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  WB analysis using 22571-1-AP (same clone as 22571-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22571-1-AP (SEMA6B antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22571-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 22571-1-AP (same clone as 22571-1-PBS)

  IP result of anti-SEMA6B (IP:22571-1-AP, 4ug; Detection:22571-1-AP 1:1000) with mouse brain tissue lysate 1120 ug. This data was developed using the same antibody clone with 22571-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22571-1-PBS cible SEMA6B dans les applications de WB, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SEMA6B Protéine recombinante Ag16707
• Nom complet: sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
• Masse moléculaire calculée: 95, 74 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC142617
• Symbole du gène: SEMA6B
• Identification du gène (NCBI): 10501
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purifié par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Semaphorins (SEMAs) play critical roles in inflammation, angiogenesis, apoptosis, fibrosis, bone remodeling, and cell invasion. SEMA6B, the sixth member of the SEMA family, has shown significant correlations with the stage of liver fibrosis in hepatitis C virus-infected patients. SEMA6B is also involved in inflammatory responses and serves as a biomarker for macrophage-specific genes. Additionally, the level of SEMA6B in circulating monocytes has predictive value for cardiovascular disease. Also, SEMA6B can be a valuable biomarker for diagnosing HBV-ACLF12 (PMID: 39267780).

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