Anticorps Polyclonal de lapin anti-SENP1

• Phare
• Validé par KD/KO

SENP1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25349-1-PBS

Synonymes

SuPr2, SuPr 2, Sentrin specific protease 1, SENP 1

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Galerie de données de validation

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  WB analysis using 25349-1-AP (same clone as 25349-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 25349-1-AP (SENP1 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25349-1-PBS in a different storage buffer formulation.

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  IP experiment of Jurkat using 25349-1-AP (same clone as 25349-1-PBS)

  IP result of anti-SENP1 (IP:25349-1-AP, 4ug; Detection:25349-1-AP 1:1000) with Jurkat cells lysate 1400 ug. This data was developed using the same antibody clone with 25349-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary cancer using 25349-1-AP (same clone as 25349-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovarian cancer slide using 25349-1-AP (SENP1 antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 25349-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 25349-1-AP (same clone as 25349-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tissue slide using 25349-1-AP (SENP1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 25349-1-PBS in a different storage buffer formulation.

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  IHC staining of human ovary using 25349-1-AP (same clone as 25349-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human ovary tissue slide using 25349-1-AP (SENP1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 25349-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 25349-1-AP (same clone as 25349-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 25349-1-AP (SENP1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 25349-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 25349-1-AP (same clone as 25349-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 25349-1-AP (SENP1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 25349-1-PBS in a different storage buffer formulation.

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  IHC staining of human testis using 25349-1-AP (same clone as 25349-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 25349-1-AP (SENP1 Antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 25349-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 25349-1-AP (same clone as 25349-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis tissue slide using 25349-1-AP (SENP1 Antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 25349-1-PBS in a different storage buffer formulation.

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Informations sur le produit

25349-1-PBS cible SENP1 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SENP1 Protéine recombinante Ag18028
• Nom complet: SUMO1/sentrin specific peptidase 1
• Masse moléculaire calculée: 644 aa, 73 kDa
• Poids moléculaire observé: 73-74 kDa
• Numéro d’acquisition GenBank: BC045639
• Symbole du gène: SENP1
• Identification du gène (NCBI): 29843
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SENP1, Sentrin-specific protease 1, is a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. SENP1 catalyzes two functions in the SUMO pathway (PMID: 29506078).The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins (PMID: 16253240). SENP1 is located in the nucleus and cytosol.

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