Anticorps Polyclonal de lapin anti-SEPT12

SEPT12 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 13707-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 13707-1-AP (same clone as 13707-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 13707-1-AP (SEPT12 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13707-1-PBS in a different storage buffer formulation.

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Informations sur le produit

13707-1-PBS cible SEPT12 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SEPT12 Protéine recombinante Ag4644
• Nom complet: septin 12
• Masse moléculaire calculée: 358 aa, 41 kDa
• Poids moléculaire observé: 41 kDa
• Numéro d’acquisition GenBank: BC035619
• Symbole du gène: SEPT12
• Identification du gène (NCBI): 124404
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SEPT12, also known as Septin 12, SPGF10, is a member of the Septin GTPase family. The Septin family is a group of evolutionarily conserved GTP-binding proteins involved in various cellular processes. SEPT12 is a cytoskeletal GTPase that is specifically enriched in the testis. It plays a critical role in spermatogenesis, particularly in the formation and maintenance of sperm tail structures. Mutations or downregulation of SEPT12 have been linked to male infertility due to defects in sperm morphology and function(PMID: 30513371).

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