Anticorps Recombinant de lapin anti-Serpin E1/PAI-1

Serpin E1/PAI-1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

243115E1

N° de cat : 85683-6-PBS

Synonymes

PAI-1, SERPINE1, SERPINE1, PAI-1, PAI, PAI 1

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Galerie de données de validation

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  WB analysis using 85683-6-RR (same clone as 85683-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85683-6-RR (SERPINE1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85683-6-PBS in a different storage buffer formulation.

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Informations sur le produit

85683-6-PBS cible Serpin E1/PAI-1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Serpin E1/PAI-1 Protéine recombinante Eg3798
• Nom complet: serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
• Masse moléculaire calculée: 402 aa, 45 kDa
• Poids moléculaire observé: 45 kDa
• Numéro d’acquisition GenBank: BC010860
• Symbole du gène: PAI-1
• Identification du gène (NCBI): 5054
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SERPINE1, also named as Plasminogen activator inhibitor type 1 (PAI-1), is a member of the serine protease inhibitor (SERPIN) superfamily. PAI-1 is the principal inhibitor of tPA and uPA, and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.

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