Anticorps Recombinant de lapin anti-SERPING1/C1 Inactivator

SERPING1/C1 Inactivator Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3H7

N° de cat : 82731-1-PBS

Synonymes

Serpin G1, SERPING1, C1-inhibiting factor, C1IN, C1 inhibiting factor

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Galerie de données de validation

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  WB analysis of human plasma using 82731-1-RR (same clone as 82731-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 82731-1-RR (SERPING1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82731-1-PBS in a different storage buffer formulation.

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Informations sur le produit

82731-1-PBS cible SERPING1/C1 Inactivator dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: SERPING1/C1 Inactivator Protéine recombinante Ag2819
• Nom complet: serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
• Masse moléculaire calculée: 500 aa, 55 kDa
• Poids moléculaire observé: 100 kDa
• Numéro d’acquisition GenBank: BC011171
• Symbole du gène: SERPING1
• Identification du gène (NCBI): 710
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein. Of its 95-105 kDa apparent molecular mass, the protein moiety of 500 aa accounts for only 55 kDa. The native 105 kDa form of C1INH could be cleaved into 60-65 kDa fragments.

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