Anticorps Monoclonal anti-SERPING1/C1 Inactivator

• Phare
• Validé par KD/KO

SERPING1/C1 Inactivator Monoclonal Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, porc, rat

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1B11B11

N° de cat : 66882-1-PBS

Synonymes

C1 esterase inhibitor, C1 Inh, C1 inhibiting factor, C1IN, C1INH, C1NH, HAE1, HAE2, Plasma protease C1 inhibitor, Serpin G1, SERPING1, SERPING1/C1 Inactivator

---

Galerie de données de validation

• 

  WB analysis using 66882-1-Ig (same clone as 66882-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66882-1-Ig (SERPING1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66882-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HeLa using 66882-1-Ig (same clone as 66882-1-PBS)

  Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using SERPING1/C1 Inactivator antibody (66882-1-Ig, Clone: 1B11B11 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L), CL594-Phalloidin (red). This data was developed using the same antibody clone with 66882-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HepG2 using 66882-1-Ig (same clone as 66882-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed HepG2 cells using SERPING1/C1 Inactivator antibody (66882-1-Ig, Clone: 1B11B11 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66882-1-PBS in a different storage buffer formulation.

• 

  IF Staining of HepG2 using 66882-1-Ig (same clone as 66882-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed HepG2 cells using SERPING1/C1 Inactivator antibody (66882-1-Ig, Clone: 1B11B11 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66882-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

66882-1-PBS cible SERPING1/C1 Inactivator dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat

• Réactivité: Humain, porc, rat
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SERPING1/C1 Inactivator Protéine recombinante Ag16782
• Nom complet: serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
• Masse moléculaire calculée: 500 aa, 55 kDa
• Poids moléculaire observé: 100 kDa
• Numéro d’acquisition GenBank: BC011171
• Symbole du gène: SERPING1
• Identification du gène (NCBI): 710
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SERPING1, also known as C1 Inhibitor (C1INH), is a member of the Serine proteinase inhibitor family. Its main function is the inhibition of the complement system to prevent spontaneous activation. It inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). C1INH is the most heavily glycosylated plasma protein.

{{ptg:RelatedPrimaryAntibodies}}