Anticorps Polyclonal de lapin anti-SFRP5

SFRP5 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 19177-1-PBS

Synonymes

Frizzled related protein 1b, Frizzled-related protein 1b, FRP1B, FRP-1b, SARP3

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Galerie de données de validation

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  IHC staining of human thyroid cancer using 19177-1-AP (same clone as 19177-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human thyroid cancer tissue slide using 19177-1-AP (SFRP5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19177-1-PBS in a different storage buffer formulation.

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  IHC staining of human cervical cancer using 19177-1-AP (same clone as 19177-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 19177-1-AP (SFRP5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19177-1-PBS in a different storage buffer formulation.

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  IHC staining of human cervical cancer using 19177-1-AP (same clone as 19177-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 19177-1-AP (SFRP5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 19177-1-PBS in a different storage buffer formulation.

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Informations sur le produit

19177-1-PBS cible SFRP5 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SFRP5 Protéine recombinante Ag5715
• Nom complet: secreted frizzled-related protein 5
• Masse moléculaire calculée: 36 kDa
• Numéro d’acquisition GenBank: BC050435
• Symbole du gène: SFRP5
• Identification du gène (NCBI): 6425
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Secreted frizzled-related protein 5 (SFRP5) is an anti-inflammatory adipokine whose expression is perturbed in models of obesity and type 2 diabetes. SFRP5 is secreted by adipocytes and that it controls the micro-environment of white adipose tissue under conditions of metabolic stress (PMID: 20558665). SFRP5 gene consists of 317 amino acid residues and 3 coding exons and maps to chromosome 10q24.1 in humans. SFRP5 was initially found to be highly expressed in retinal pigment epithelium cells and moderately expressed in the pancreas. SFRP5 is involved in the pathological process of obesity, insulin resistance, dyslipidemia, inflammation, and fibrosis and is associated with obesity, T2D, and ASCVD (PMID: 31199714, PMID: 32004418).

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