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Anticorps Polyclonal de lapin anti-SFRS2

SFRS2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21212-1-PBS

Synonymes

Serine/arginine-rich splicing factor 2, SC-35, SC35, SC 35, Protein PR264

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using SFRS2 Polyclonal antibody (21212-1-AP)

    WB analysis using 21212-1-AP (same clone as 21212-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21212-1-AP (SFRS2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21212-1-PBS in a different storage buffer formulation.

Informations sur le produit

21212-1-PBS cible SFRS2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène SFRS2 Protéine recombinante Ag15612
Nom complet splicing factor, arginine/serine-rich 2
Masse moléculaire calculée 221 aa, 25 kDa
Poids moléculaire observé30-35 kDa
Numéro d’acquisition GenBankBC070086
Symbole du gène SFRS2
Identification du gène (NCBI) 6427
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SFRS2, also named as PR264 and SC-35, belongs to the splicing factor SR family. SFRS2 is necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. It binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. SFRS2 can bind to beta-globin mRNA and commit it to the splicing pathway. The antibody has no cross reaction to SFRS2B.

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