Anticorps Polyclonal de lapin anti-SGLT3/SLC5A4

SGLT3/SLC5A4 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24327-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of mouse kidney using 24327-1-AP (same clone as 24327-1-PBS)

  mouse kidney tissue were subjected to SDS PAGE followed by western blot with 24327-1-AP (SGLT3/SLC5A4 antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24327-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse kidney using 24327-1-AP (same clone as 24327-1-PBS)

  IP result of anti-SGLT3/SLC5A4 (IP:24327-1-AP, 4ug; Detection:24327-1-AP 1:500) with mouse kidney tissue lysate 4000ug. This data was developed using the same antibody clone with 24327-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 24327-1-AP (same clone as 24327-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney slide using 24327-1-AP (SGLT3/SLC5A4 antibody at dilution of 1:50. This data was developed using the same antibody clone with 24327-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 24327-1-AP (same clone as 24327-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney slide using 24327-1-AP (SGLT3/SLC5A4 antibody at dilution of 1:50. This data was developed using the same antibody clone with 24327-1-PBS in a different storage buffer formulation.

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Informations sur le produit

24327-1-PBS cible SGLT3/SLC5A4 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SGLT3/SLC5A4 Protéine recombinante Ag19391
• Nom complet: solute carrier family 5 (low affinity glucose cotransporter), member 4
• Masse moléculaire calculée: 659 aa, 72 kDa
• Poids moléculaire observé: 60-70 kDa
• Numéro d’acquisition GenBank: BC153069
• Symbole du gène: SGLT3
• Identification du gène (NCBI): 6527
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC5A4, also known as SGLT3, is a sugar sensor that depolarizes the plasma membrane in response to external glucose (PMID: 12748858, 20421923). SGLT3 mediates the influx of sodium ions into the cell but does not transport sugars, also potently activated by imino sugars such as deoxynojirimycin (PMID: 22766068, 13130073). SGLT3 is a plasma membrane protein, shares 70% identity with SGLT1, and is expressed in the small intestine (cholinergic neurons), skeletal muscle, kidney, uterus, and testis (PMID: 12748858). SGLT3 protein at apparent molecular masses of 72 kDa and 80 kDa in human kidney tissue and HK-2 cells (PMID: 22766068).

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