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Anticorps Polyclonal de lapin anti-SH2D1A

SH2D1A Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 11868-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of mouse thymus tissue using SH2D1A Polyclonal antibody (11868-1-AP)

    WB analysis of mouse thymus using 11868-1-AP (same clone as 11868-1-PBS)

    mouse thymus tissue were subjected to SDS PAGE followed by western blot with 11868-1-AP (SH2D1A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11868-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Jurkat cells using SH2D1A Polyclonal antibody (11868-1-AP)

    WB analysis of Jurkat using 11868-1-AP (same clone as 11868-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 11868-1-AP (SH2D1A Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11868-1-PBS in a different storage buffer formulation.

Informations sur le produit

11868-1-PBS cible SH2D1A dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène SH2D1A Protéine recombinante Ag2450
Nom complet SH2 domain protein 1A
Masse moléculaire calculée 128 aa, 14 kDa
Poids moléculaire observé 16 kDa
Numéro d’acquisition GenBankBC020732
Symbole du gène SH2D1A
Identification du gène (NCBI) 4068
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SH2D1A, also named as DSHP and SAP, is an inhibitor of the SLAM self-association. It acts by blocking recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to a docking site in the SLAM cytoplasmic region. SH2D1A mediates interaction between FYN and SLAMF1. Defects in SH2D1A are a cause of lymphoproliferative syndrome X-linked type 1 (XLP1).

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