Anticorps Monoclonal anti-SHARPIN

SHARPIN Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3A9E2

N° de cat : 67177-1-PBS

Synonymes

DKFZp434N1923, hSIPL1, SHARPIN, SIPL1

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Galerie de données de validation

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  WB analysis using 67177-1-Ig (same clone as 67177-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67177-1-Ig (SHARPIN antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67177-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 67177-1-Ig (same clone as 67177-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67177-1-Ig (SHARPIN antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67177-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67177-1-PBS cible SHARPIN dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SHARPIN Protéine recombinante Ag6367
• Nom complet: SHANK-associated RH domain interactor
• Masse moléculaire calculée: 40 kDa
• Poids moléculaire observé: 40 kDa
• Numéro d’acquisition GenBank: BC025244
• Symbole du gène: SHARPIN
• Identification du gène (NCBI): 81858
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SHARPIN is as a third component of the linear ubiquitin chain assembly complex (LUBAC), recruited to the CD40 and TNF receptor signaling complexes together with its other constituents, HOIL1 and HOIP(PMID:21455173).SHARPIN is enriched in the postsynaptic density and forms a complex with SHANK in heterologous cells and brain(PMID:11178875).It has 2 isoforms produced by alternative splicing.

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