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Anticorps Polyclonal de lapin anti-SHB

SHB Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31967-1-PBS

Synonymes

SH2 domain-containing adapter protein B

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using SHB Polyclonal antibody (31967-1-AP)

    WB analysis using 31967-1-AP (same clone as 31967-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31967-1-AP (SHB antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31967-1-PBS in a different storage buffer formulation.

Informations sur le produit

31967-1-PBS cible SHB dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

Réactivité Humain, rat, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène SHB Protéine recombinante Ag35936
Nom complet Src homology 2 domain containing adaptor protein B
Masse moléculaire calculée55 kDa
Poids moléculaire observé55 kDa
Numéro d’acquisition GenBankBC136581
Symbole du gène SHB
Identification du gène (NCBI) 6461
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SH2 domain-containing adapter protein B (SHB) is an adaptor protein that operates downstream of tyrosine kinases. It is crucial in various cellular responses, including cell survival, differentiation, and proliferation (PMID: 29792386). SHB is involved in the modulation of focal adhesion kinase (FAK) signaling, which is important for regulating cell cycle progression in hematopoietic stem cells (PMID: 23528453). The protein has also been implicated in the progression of myeloproliferative disorders by affecting the activity of FAK and other signaling intermediates (PMID: 24952416).

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