Anticorps Polyclonal de lapin anti-SHBG

SHBG Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 18200-1-PBS

Synonymes

Testosterone-estradiol-binding globulin, Testis-specific androgen-binding protein, Sex steroid-binding protein, Sex steroid binding protein, Sex hormone-binding globulin

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Galerie de données de validation

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  WB analysis using 18200-1-AP (same clone as 18200-1-PBS)

  human plasma were subjected to SDS PAGE followed by western blot with 18200-1-AP (SHBG antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18200-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 18200-1-AP (same clone as 18200-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 18200-1-AP (SHBG antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18200-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 18200-1-AP (same clone as 18200-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 18200-1-AP (SHBG antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 18200-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18200-1-PBS cible SHBG dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SHBG Protéine recombinante Ag12683
• Nom complet: sex hormone-binding globulin
• Masse moléculaire calculée: 402 aa, 44 kDa
• Poids moléculaire observé: 42-44 kDa
• Numéro d’acquisition GenBank: BC101785
• Symbole du gène: SHBG
• Identification du gène (NCBI): 6462
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SHBG (sex hormone-binding globulin), also known as androgen-binding protein (ABP), is the specific transport protein for sex steroid hormones in humans. SHBG is synthesized mainly by the liver and circulates in the blood, in form of homodimer with a single steroid-binding site per dimer. In addition to the plasma SHBG, a testis isoform expressed by Sortoli cells also exists due to the gene alternative splicing. Various bands (44-56 kDa) recognized by this antibody may represent variably glycosylated or different isoforms of SHBG.

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