Anticorps Monoclonal anti-SHC1

SHC1 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Mouse / IgG2b

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1A5B1

N° de cat : 67194-2-PBS

Synonymes

SHC, 1A5B1, SH2 domain protein C1, SHC transforming protein 1, SHC-transforming protein 1

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Galerie de données de validation

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  WB analysis using 67194-2-Ig (same clone as 67194-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67194-2-Ig (SHC1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67194-2-PBS in a different storage buffer formulation.

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  WB analysis of hTERT-RPE1 using 67194-2-Ig (same clone as 67194-2-PBS)

  hTERT-RPE1 cells were subjected to SDS PAGE followed by western blot with 67194-2-Ig (SHC1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67194-2-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP50763-1

  Cytometric bead array standard curve of MP50763-1, SHC1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67194-2-PBS. Detection antibody: 67194-3-PBS. Standard:Ag25173. Range: 0.098-100 ng/mL.

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  Cytometric bead array standard curve of MP50763-3

  Cytometric bead array standard curve of MP50763-3, SHC1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 67194-2-PBS. Detection antibody: 67194-4-PBS. Standard:Ag25173. Range: 0.391-50 ng/mL.

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Informations sur le produit

67194-2-PBS cible SHC1 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2b
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SHC1 Protéine recombinante Ag25173
• Nom complet: SHC (Src homology 2 domain containing) transforming protein 1
• Masse moléculaire calculée: 63 kDa
• Poids moléculaire observé: 66 kDa
• Numéro d’acquisition GenBank: NM_183001
• Symbole du gène: SHC1
• Identification du gène (NCBI): 6464
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The proto-oncogene SHC family consists of SHCA, SHCB, SHCC, and SHCD4 gene members, which can encode 7 kinds of cohesive molecules. SHC family is widely expressed and functional. The SHC1 gene is located in zone 1, region 2 of human chromosome 1. SHC1 is believed to be involved in inhibiting neuronal apoptosis and regulating the receptor tyrosine kinase pathway. SHC1 sensitizes cancer cells to the 8-Cl-cAMP treatment.

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