Anticorps Polyclonal de lapin anti-SKOR2

SKOR2 Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55370-1-PBS

Synonymes

---

Galerie de données de validation

• 

  WB analysis using 55370-1-AP (same clone as 55370-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 55370-1-AP (SKOR2 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55370-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse cerebellum using 55370-1-AP (same clone as 55370-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 55370-1-AP (SKOR2 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55370-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse cerebellum using 55370-1-AP (same clone as 55370-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 55370-1-AP (SKOR2 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55370-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse cerebellum using 55370-1-AP (same clone as 55370-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse cerebellum tissue using SKOR2 antibody (55370-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 55370-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

55370-1-PBS cible SKOR2 dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: functional smad suppressing element 18
• Masse moléculaire calculée: 104 kDa
• Poids moléculaire observé: 30kDa, 60 kDa
• Numéro d’acquisition GenBank: XM_001715219
• Symbole du gène: SKOR2
• Identification du gène (NCBI): 652991
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SKOR2 (SKI family transcriptional corepressor 2), also named FUSSEL18, is a transcriptional repressor that is highly expressed in the central nervous system (PMID: 16200078). SKOR2 was detected at 30 and 60 kD in the cerebellum. It is identified as a novel transcriptional regulator in Purkinje cells that acts upstream of Shh during cerebellum development (PMID: 21937600). Skor2 was detected in Purkinje cells in the human fetal cerebellum (PMID: 34140698).

{{ptg:RelatedPrimaryAntibodies}}