Anticorps Recombinant de lapin anti-SLAM/CD150

SLAM/CD150 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241800B12

N° de cat : 98220-1-PBS

Synonymes

SLAMF1, SLAM family member 1, SLAM, IPO-3, IPO 3

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Galerie de données de validation

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  FC experiment of human PBMCs using 98220-1-RR (same clone as 98220-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human SLAM/CD150 Rabbit Recombinant Antibody (98220-1-RR, Clone: 241800B12) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98220-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98220-1-RR (same clone as 98220-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human SLAM/CD150 Rabbit Recombinant Antibody (98220-1-RR, Clone: 241800B12) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98220-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98220-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98220-1-RR against Human SLAM/CD150 were performed. The affinity constant is 3.16 nM.

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Informations sur le produit

98220-1-PBS cible SLAM/CD150 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: signaling lymphocytic activation molecule family member 1
• Masse moléculaire calculée: 37kDa
• Numéro d’acquisition GenBank: NM_003037.5
• Symbole du gène: CD150
• Identification du gène (NCBI): 6504
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Signaling lymphocytic activation molecule (SLAM, also known as SLAMF1 or CD150) is a 70-95 kDa transmembrane glycoprotein that belongs to the immunoglobulin gene superfamily. SLAM is constitutively expressed on peripheral blood memory T-cells, T-cell clones, immature thymocytes and a proportion of B-cells, and is rapidly induced on naive T-cells after activation. SLAM is involved in T cell stimulation and cytokine production, and may play an important role in the regulation of immune responses to pathogens.

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