Anticorps Recombinant de lapin anti-SLAMF6

SLAMF6 Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251099E10

N° de cat : 86422-1-PBS

Synonymes

CD352, Ly108, Lymphocyte antigen 108, SLAM family member 6

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Galerie de données de validation

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  WB analysis using 86422-1-RR (same clone as 86422-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86422-1-RR (SLAMF6/CD352 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86422-1-PBS in a different storage buffer formulation.

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  IF Staining of A20 using 86422-1-RR (same clone as 86422-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A20 cells using SLAMF6 antibody (86422-1-RR, Clone: 251099E10 ) at dilution of 1:500 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 86422-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86422-1-PBS cible SLAMF6 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: SLAMF6 Protéine recombinante Eg5249
• Nom complet: SLAM family member 6
• Masse moléculaire calculée: 36 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: NM_030710.2
• Symbole du gène: Slamf6
• Identification du gène (NCBI): 30925
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Signaling lymphocyte activation molecule 6 (SLAMF6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules (PMID:31199820). SLAMF6 is a type I transmembrane protein with two extracellular immunoglobins (Ig)-like domains and three cytoplasmic tyrosine-based signaling motifs, one of which is immunoreceptor tyrosine-based switch motif (PMID:31315913). SLAMF6 is expressed on a wide variety of immune cells including T cells (also TFH), B cells, NK cells (expressed in humans only), double positive thymocytes, eosinophils, and neutrophils (mouse only) (PMID:11862385).

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