Anticorps Polyclonal de lapin anti-SLC12A3/NCCT

SLC12A3/NCCT Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55442-1-PBS

Synonymes

SLC12A3, NCCT

---

Galerie de données de validation

• 

  WB analysis using 55442-1-AP (same clone as 55442-1-PBS)

  37°C incubated mouse kidney tissue were subjected to SDS PAGE followed by western blot with 55442-1-AP (SLC12A3/NCCT antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55442-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

55442-1-PBS cible SLC12A3/NCCT dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: solute carrier family 12 (sodium/chloride transporters), member 3
• Masse moléculaire calculée: 114 kDa
• Poids moléculaire observé: 150 kDa
• Numéro d’acquisition GenBank: NM_000339
• Symbole du gène: SLC12A3
• Identification du gène (NCBI): 6559
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC12A3 also known as NCCT, NCC, is a sodium-chloride cotransporter (NCC), which mainly functions in the distal convoluted tubules of the kidney and is responsible for the reabsorption of sodium ions and chloride ions (PMID: 35591852). This cotransporter is the target of thiazide diuretics used in the treatment of hypertension. Mutations in SLC12A3 cause Gitelman syndrome(PMID: 8528245, 33462018).

{{ptg:RelatedPrimaryAntibodies}}