Anticorps Recombinant de lapin anti-MCT2/SLC16A7

MCT2/SLC16A7 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242811F6

N° de cat : 85145-3-PBS

Synonymes

SLC16A7, MCT 2, MCT2, Monocarboxylate transporter 2, Solute carrier family 16 member 7

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Galerie de données de validation

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  WB analysis using 85145-3-RR (same clone as 85145-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85145-3-RR (SLC16A7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85145-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 85145-3-RR

  Biolayer interferometry (BLl) kinetic assays of 85145-3-RR against Human MCT2/SLC16A7 were performed. The affinity constant is 37.0 nM.

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Informations sur le produit

85145-3-PBS cible MCT2/SLC16A7 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: MCT2/SLC16A7 Protéine recombinante Ag14201
• Nom complet: solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
• Masse moléculaire calculée: 478 aa, 52 kDa
• Poids moléculaire observé: 40-52 kDa
• Numéro d’acquisition GenBank: BC030693
• Symbole du gène: MCT2
• Identification du gène (NCBI): 9194
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC16A7, also named MCT2, is a proton-coupled monocarboxylate transporter catalyzing the rapid transport across the plasma membrane of many monocarboxylates. It has been reported that SLC16A7 is the primary monocarboxylate transporter in Purkinje cells and can be detected in the brain, cerebellum, liver, and kidney, but not in vascular smooth muscle cells, pericytes, endothelium, heart, lung, or stomach. There are some isoforms of SLC16A7 with bands around 52 kDa and 40-45 kDa in SDS-PAGE. The 80 kDa protein might be a dimer, similar to the papers published. (PMID: 9482213, 15749979, 11291733, 16901736)

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