Anticorps Polyclonal de lapin anti-SLC22A16

SLC22A16 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 26833-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 26833-1-AP (same clone as 26833-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 26833-1-AP (SLC22A16 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 26833-1-AP (same clone as 26833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 26833-1-AP (SLC22A16 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 26833-1-AP (same clone as 26833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 26833-1-AP (SLC22A16 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human stomach cancer using 26833-1-AP (same clone as 26833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 26833-1-AP (SLC22A16 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 26833-1-AP (same clone as 26833-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 26833-1-AP (SLC22A16 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

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  IF Staining of THP-1 using 26833-1-AP (same clone as 26833-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed THP-1 cells using SLC22A16 antibody (26833-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26833-1-PBS in a different storage buffer formulation.

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Informations sur le produit

26833-1-PBS cible SLC22A16 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC22A16 Protéine recombinante Ag25270
• Nom complet: solute carrier family 22 (organic cation/carnitine transporter), member 16
• Masse moléculaire calculée: 65 kDa
• Poids moléculaire observé: 68 kDa
• Numéro d’acquisition GenBank: BC047565
• Symbole du gène: SLC22A16
• Identification du gène (NCBI): 85413
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC22A16, also named as CT2, FLIPT2, or OCT6, belongs to the major facilitator (TC 2.A.1) superfamily and organic cation transporter (TC 2.A.1.19) family. SLC22A16 encodes an organic zwitterion transporter protein that transports carnitine and some anticancer drugs, including anthracyclines. As a carnitine transporter, SLC22A16 is involved in the regulation of fatty acid oxidation (FAO), which plays an important role also in the metabolic transformation of cancer cells. SLC22A16 expression in cancer cells is associated with increased sensitivity to the cytotoxic effects of doxorubicin. SLC22A16 has 3 isoforms with the molecular mass of 58, 61 and 65 kDa (PMID: 35761855, 35608746).

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