Anticorps Monoclonal anti-SLC22A7

SLC22A7 Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3D3C3

N° de cat : 67479-1-PBS

Synonymes

SLC22A7, 3D3C3, hOAT2, NLT, OAT2

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Galerie de données de validation

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  WB analysis of SMMC-7721 using 67479-1-Ig (same clone as 67479-1-PBS)

  SMMC-7721 cells were subjected to SDS PAGE followed by western blot with 67479-1-Ig (SLC22A7 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67479-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 67479-1-Ig (same clone as 67479-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67479-1-Ig (SLC22A7 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67479-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 67479-1-Ig (same clone as 67479-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67479-1-Ig (SLC22A7 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67479-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver using 67479-1-Ig (same clone as 67479-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 67479-1-Ig (SLC22A7 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67479-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse liver using 67479-1-Ig (same clone as 67479-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 67479-1-Ig (SLC22A7 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67479-1-PBS in a different storage buffer formulation.

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Informations sur le produit

67479-1-PBS cible SLC22A7 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: SLC22A7 Protéine recombinante Ag25234
• Nom complet: solute carrier family 22 (organic anion transporter), member 7
• Masse moléculaire calculée: 60 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC033805
• Symbole du gène: SLC22A7
• Identification du gène (NCBI): 10864
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Organic anion transporter (OAT)2 (SLC22A7) belongs to the solute carrier group of membrane transport proteins that mediate cellular uptake of numerous organic ions including xenobiotics and endogenous substrates (PMID: 9529348, 20190416). SLC22A7 was originally identified as a novel liver-specific transporter because of its predominant mRNA expression in the rat liver (PMID: 15900017, 25904762). Human SLC22A7 exhibits a robust transport function for a wide array of naturally occurring nucleobases, nucleosides, and nucleotides with a particular role for cGMP (PMID: 18216183).

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