Anticorps Polyclonal de lapin anti-SLC24A3

SLC24A3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27591-1-PBS

Synonymes

NCKX3

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Galerie de données de validation

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  WB analysis using 27591-1-AP (same clone as 27591-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27591-1-AP (SLC24A3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27591-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27591-1-PBS cible SLC24A3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC24A3 Protéine recombinante Ag26297
• Nom complet: solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
• Masse moléculaire calculée: 72 kDa
• Poids moléculaire observé: 50-60 kDa
• Numéro d’acquisition GenBank: NM_020689
• Symbole du gène: SLC24A3
• Identification du gène (NCBI): 57419
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC24A3, also known as NCKX3 (Na⁺/K⁺/Ca²⁺ exchanger 3), is a member of the solute carrier family 24 (SLC24), which comprises five K⁺-dependent Na⁺/Ca²⁺ exchangers (NCKX1-5). These transporters are critical for maintaining intracellular calcium homeostasis by coupling the extrusion of one Ca²⁺ ion and one K⁺ ion to the influx of four Na⁺ ions. SLC24A3 plays a key role in calcium signaling and homeostasis, influencing processes such as neurotransmission, smooth muscle contraction, and female reproductive physiology. Relatively high levels of SLC24A3 expression can be observed in heart tissue, consistent with the expression patterns reported in the literature. The observed molecular weight of SLC24A3 is 50-60 kDa, which is consistent with the literature description. (PMID: 21573014, PMID: 28588505)

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