Anticorps Polyclonal de lapin anti-SLC24A6

• Phare
• Validé par KD/KO

SLC24A6 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 21430-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 21430-1-AP (same clone as 21430-1-PBS)

  Mouse brain tissue were subjected to SDS PAGE followed by western blot with 21430-1-AP (SLC24A6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

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  WB analysis using 21430-1-AP (same clone as 21430-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 21430-1-AP (SLC24A6 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse heart using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse heart using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse heart tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 21430-1-AP (same clone as 21430-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 21430-1-AP (SLC24A6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 21430-1-PBS in a different storage buffer formulation.

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Informations sur le produit

21430-1-PBS cible SLC24A6 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC24A6 Protéine recombinante Ag16034
• Nom complet: solute carrier family 24 (sodium/potassium/calcium exchanger), member 6
• Masse moléculaire calculée: 584 aa, 64 kDa
• Poids moléculaire observé: 64 kDa
• Numéro d’acquisition GenBank: BC098360
• Symbole du gène: SLC24A6
• Identification du gène (NCBI): 80024
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC24A6, also named as NCLX, is a kind of mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion by mediating the exchange of 3 sodium ions per 1 calcium ion. It has been reported that SLC24A6 plays a key role in attenuating potential ROS production and injury upon cardiac reperfusion. SLC24A6 is associated with mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion. (PMID: 32728214, 20018762, 28219928)

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