Anticorps Recombinant de lapin anti-SLC25A1

• Phare
• Validé par KD/KO

SLC25A1 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241931G11

N° de cat : 84696-1-PBS

Synonymes

Tricarboxylate carrier protein, SLC20A3, CTP, Citrate transport protein, CIC

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Galerie de données de validation

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  WB analysis using 84696-1-RR (same clone as 84696-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84696-1-RR (SLC25A1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84696-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 84696-1-RR (same clone as 84696-1-PBS)

  WB result of SLC25A1 antibody (84696-1-RR; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SLC25A1 transfected HeLa cells. This data was developed using the same antibody clone with 84696-1-PBS in a different storage buffer formulation.

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Informations sur le produit

84696-1-PBS cible SLC25A1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
• Masse moléculaire calculée: 34 kDa
• Poids moléculaire observé: 30 kDa
• Numéro d’acquisition GenBank: BC004980
• Symbole du gène: SLC25A1
• Identification du gène (NCBI): 6576
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC25A1, also known as CIC or CTP, is a mitochondrial citrate transporter that exports citrate from the mitochondria to the cytosol. SLC25A1 is highly expressed in several tumor types. Recently it has been identified as a novel transcriptional target of mutant p53 and a negative tumor prognostic marker. In addition, defects in SLC25A1 have been found as a cause of combined D-2- and L-2-hydroxyglutaric aciduria. (PMID: 24681808, 23561848)

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