Anticorps Polyclonal de lapin anti-SLC25A12

SLC25A12 Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 26804-1-PBS

Synonymes

AGC1, Araceli hiperlarga, Aralar, Aralar1, Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

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Galerie de données de validation

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  WB analysis using 26804-1-AP (same clone as 26804-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 26804-1-AP (SLC25A12 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 26804-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 26804-1-AP (same clone as 26804-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 26804-1-AP (SLC25A12 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26804-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 26804-1-AP (same clone as 26804-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 26804-1-AP (SLC25A12 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26804-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas cancer using 26804-1-AP (same clone as 26804-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 26804-1-AP (SLC25A12 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26804-1-PBS in a different storage buffer formulation.

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  IHC staining of human pancreas cancer using 26804-1-AP (same clone as 26804-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 26804-1-AP (SLC25A12 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26804-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 26804-1-AP (same clone as 26804-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 26804-1-AP (SLC25A12 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26804-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 26804-1-AP (same clone as 26804-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 26804-1-AP (SLC25A12 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26804-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 26804-1-AP (same clone as 26804-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 26804-1-AP (SLC25A12 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26804-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse kidney using 26804-1-AP (same clone as 26804-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 26804-1-AP (SLC25A12 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 26804-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse heart using 26804-1-AP (same clone as 26804-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed tissue using 26804-1-AP (SLC25A12 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 26804-1-PBS in a different storage buffer formulation.

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Informations sur le produit

26804-1-PBS cible SLC25A12 dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC25A12 Protéine recombinante Ag25150
• Nom complet: solute carrier family 25 (mitochondrial carrier, Aralar), member 12
• Masse moléculaire calculée: 75 kDa, 63 kDa
• Poids moléculaire observé: ~70 kDa
• Numéro d’acquisition GenBank: BC016932
• Symbole du gène: SLC25A12
• Identification du gène (NCBI): 8604
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC25A12, also known as ARALAR1, is a key component of the malate-aspartate shuttle, a metabolic system that facilitates the transfer of reducing equivalents (NADH) from the cytoplasm into mitochondria, thereby supporting oxidative phosphorylation and ATP production. SLC25A12 dysfunction results in impaired mitochondrial energy production, which can lead to neuronal damage, developmental delays, and myelination defects (PMID: 20015484).

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