Anticorps Polyclonal de lapin anti-SLC25A23

SLC25A23 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20168-1-PBS

Synonymes

APC2, MCSC2, Mitochondrial adenyl nucleotide antiporter SLC25A23, Mitochondrial ATP-Mg/Pi carrier protein 2, SCaMC 3

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Galerie de données de validation

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  WB analysis of mouse pancreas using 20168-1-AP (same clone as 20168-1-PBS)

  mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 20168-1-AP (SLC25A23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20168-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse testis using 20168-1-AP (same clone as 20168-1-PBS)

  mouse testis tissue were subjected to SDS PAGE followed by western blot with 20168-1-AP (SLC25A23 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20168-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse skeletal muscle using 20168-1-AP (same clone as 20168-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 20168-1-AP (SLC25A23 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20168-1-PBS in a different storage buffer formulation.

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  WB analysis of SH-SY5Y using 20168-1-AP (same clone as 20168-1-PBS)

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 20168-1-AP (SLC25A23 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20168-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20168-1-PBS cible SLC25A23 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC25A23 Protéine recombinante Ag13987
• Nom complet: solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
• Masse moléculaire calculée: 468 aa, 52 kDa
• Poids moléculaire observé: 49-54 kDa
• Numéro d’acquisition GenBank: BC001656
• Symbole du gène: SLC25A23
• Identification du gène (NCBI): 79085
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC25A23 gene encodes a 468 amino acids polypeptide, named SCaMC-3, with a bipartite structure typical of calcium-binding mitochondrial solute carrier (CaMSC) proteins. The amino-terminal portion harbors three canonical EF-hand calcium-binding domains while the carboxyl-terminal portion of SCaMC-3 has the characteristic features of the mitochondrial solute carrier (MSC) superfamily. Northern blot analysis reveals the presence of the transcript in brain, heart, skeletal muscle, liver and small intestine. The SLC25A23 gene undergoes alternative splicing suggesting a modular nature of the encoded product. Three out of four putative protein isoforms lack a significant portion of the third mitochondrial carrier signature. The most common SCaMC-3 isoform shows a mitochondrial subcellular localization when transfected in HeLa cells and is able to bind calcium by Ca2+ dependent mobility shift assays.(PMID: 15716113)

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