Anticorps Polyclonal de lapin anti-SLC30A1

SLC30A1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IHC, ELISA

Conjugaison

Non conjugué

Publications(1)

Avis (2)

N° de cat : 22661-1-AP

Synonymes

Zinc transporter 1, ZNT1, ZnT-1

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Galerie de données de validation

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  WB analysis using 22661-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 22661-1-AP (SLC30A1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: cellules HeLa, HeLa membrane protein, HepG2 total crude protein, HepG2 membrane protein

Dilution recommandée

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• IHC: See 1 publications below

Informations sur le produit

22661-1-AP cible SLC30A1 dans les applications de WB, IHC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC30A1 Protéine recombinante Ag18567
• Nom complet: solute carrier family 30 (zinc transporter), member 1
• Masse moléculaire calculée: 507 aa, 55 kDa
• Poids moléculaire observé: 63~75 kDa
• Numéro d’acquisition GenBank: BC121015
• Symbole du gène: SLC30A1
• Identification du gène (NCBI): 7779
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Zinc transporter 1 (ZNT1), also known as SLC30A1, is the only zinc transporter predominantly located on the plasma membrane, where it plays a pivotal role exporting cytosolic zinc to the extracellular space. SLC30A1 expression is posttranslationally regulated by cellular zinc status and can be N-glycosylated on Asn299 in the extracellular loop between transmembrane domains (PMID: 15451416, 18936201). ZnT1 is located in the plasma membrane and is responsible for Zn export from the cytosol to the extracellular space during periods of elevated cytosolic Zn. Western analysis detected a higher band at∼63 kDa than the expected molecular mass, which could be attributed to the properties of the cytosolic histidine-rich loop (PMID: 31471319, 15753530).

Publications

Species	Application	Title
human	IHC	Eur J Histochem; HPV infection upregulates the expression of ZNT-1 in condyloma acuminatum.; Authors - Li Niu

Avis

The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.

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FH

James (Verified Customer) (10-01-2025)

Excellent antibody. Have used at 1:2000 for Western blotting, detection by chemiluminescence.

• Applications: Western Blot
• Primary Antibody Dilution: 1:2000
• Cell Tissue Type: Human In vitro Cancer Cells

FH

David (Verified Customer) (09-15-2025)

Concentration used 1:5000. works pretty good. Strong clean signal.

• Applications: Western Blot

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