Anticorps Polyclonal de lapin anti-SLC30A1

SLC30A1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22661-1-PBS

Synonymes

Zinc transporter 1, ZNT1, ZnT-1

---

Galerie de données de validation

• 

  WB analysis using 22661-1-AP (same clone as 22661-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22661-1-AP (SLC30A1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22661-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

22661-1-PBS cible SLC30A1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC30A1 Protéine recombinante Ag18567
• Nom complet: solute carrier family 30 (zinc transporter), member 1
• Masse moléculaire calculée: 507 aa, 55 kDa
• Poids moléculaire observé: 63~75 kDa
• Numéro d’acquisition GenBank: BC121015
• Symbole du gène: SLC30A1
• Identification du gène (NCBI): 7779
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Zinc transporter 1 (ZNT1), also known as SLC30A1, is the only zinc transporter predominantly located on the plasma membrane, where it plays a pivotal role exporting cytosolic zinc to the extracellular space. SLC30A1 expression is posttranslationally regulated by cellular zinc status and can be N-glycosylated on Asn299 in the extracellular loop between transmembrane domains (PMID: 15451416, 18936201). ZnT1 is located in the plasma membrane and is responsible for Zn export from the cytosol to the extracellular space during periods of elevated cytosolic Zn. Western analysis detected a higher band at∼63 kDa than the expected molecular mass, which could be attributed to the properties of the cytosolic histidine-rich loop (PMID: 31471319, 15753530).

{{ptg:RelatedPrimaryAntibodies}}