Anticorps Polyclonal de lapin anti-SLC6A19

SLC6A19 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 29372-1-PBS

Synonymes

Sodium-dependent neutral amino acid transporter B(0)AT1, HND, B0AT1

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Galerie de données de validation

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  WB analysis using 29372-1-AP (same clone as 29372-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29372-1-AP (SLC6A19 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29372-1-PBS in a different storage buffer formulation.

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  WB analysis using 29372-1-AP (same clone as 29372-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 29372-1-AP (SLC6A19 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 29372-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 29372-1-AP (same clone as 29372-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 29372-1-AP (SLC6A19 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29372-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 29372-1-AP (same clone as 29372-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 29372-1-AP (SLC6A19 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 29372-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 29372-1-AP (same clone as 29372-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 29372-1-AP (SLC6A19 antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 29372-1-PBS in a different storage buffer formulation.

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  IHC staining of human small intestine using 29372-1-AP (same clone as 29372-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 29372-1-AP (SLC6A19 antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 29372-1-PBS in a different storage buffer formulation.

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Informations sur le produit

29372-1-PBS cible SLC6A19 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC6A19 Protéine recombinante Ag31076
• Nom complet: solute carrier family 6 (neutral amino acid transporter), member 19
• Masse moléculaire calculée: 634 aa, 71 kDa
• Poids moléculaire observé: 71 kDa
• Numéro d’acquisition GenBank: BC148801
• Symbole du gène: SLC6A19
• Identification du gène (NCBI): 340024
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC6A19, also named as B0AT1, encodes system B(0) transmembrane protein that mediates epithelial resorption of neutral amino acids across the apical membrane in kidney and intestine (PubMed: 15044460). The protein contains 634 amino acids and has 12 predicted transmembrane regions with highly expression in human kidney and small intestine and minimal in pancreas (PubMed: 15286787). The expression of SLC6A19 in intestinal cells depends on angiotensin converting enzyme 2 which is the cellular receptor for SARS-CoV-2 (PubMed: 32132184). Mutations in SLC6A19 cause Hartnup disease (PMID: 15286787, PMID: 15286788).

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