Anticorps Polyclonal de lapin anti-SLC6A20

SLC6A20 Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30843-1-PBS

Synonymes

SIT1, Sodium- and chloride-dependent transporter XTRP3, Sodium/imino-acid transporter 1, XT3, XTRP3

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Galerie de données de validation

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  WB analysis using 30843-1-AP (same clone as 30843-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30843-1-AP (SLC6A20 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30843-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse small intestine using 30843-1-AP (same clone as 30843-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue slide using 30843-1-AP (SLC6A20 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30843-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 30843-1-AP (same clone as 30843-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using SLC6A20 antibody (30843-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30843-1-PBS in a different storage buffer formulation.

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  IF Staining of mouse brain using 30843-1-AP (same clone as 30843-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse brain tissue using SLC6A20 antibody (30843-1-AP) at dilution of 1:200 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30843-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30843-1-PBS cible SLC6A20 dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC6A20 Protéine recombinante Ag33967
• Nom complet: solute carrier family 6 (proline IMINO transporter), member 20
• Poids moléculaire observé: 50-60 kDa
• Numéro d’acquisition GenBank: BC136431
• Symbole du gène: SLC6A20
• Identification du gène (NCBI): 54716
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC6A20 also known as XT3, SIT1, belongs to the family of solute carrier 6, mediating the transport of neutral amino acids from the extracellular milieu toward cell or storage vesicles utilizing an electric membrane potential as the driving force. SLC6A20 is expressed in the kidney and small intestine and is localized in the brush marginal membrane of the proximal renal tubules (PMID: 16174864). Mutations in SLC6A20 are associated with Hyperglycinuria and Iminoglycinuria (PMID: 19033659)

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