Anticorps Recombinant de lapin anti-SLC6A7

SLC6A7 Recombinant Antibody for IHC, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

IHC, ELISA

Conjugaison

Non conjugué

CloneNo.

240395H5

N° de cat : 83412-4-PBS

Synonymes

Sodium-dependent proline transporter, PROT, 240395H5

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Galerie de données de validation

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  IHC staining of mouse brain using 83412-4-RR (same clone as 83412-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 83412-4-RR (same clone as 83412-4-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 83412-4-RR (same clone as 83412-4-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 83412-4-RR (same clone as 83412-4-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 83412-4-RR (SLC6A7 antibody) at dilution of 1:400 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83412-4-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 83412-4-RR

  Biolayer interferometry (BLl) kinetic assays of 83412-4-RR against Human SLC6A7 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

83412-4-PBS cible SLC6A7 dans les applications de IHC, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: SLC6A7 Protéine recombinante Ag34413
• Nom complet: solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
• Masse moléculaire calculée: 636 aa, 71 kDa
• Numéro d’acquisition GenBank: BC093785
• Symbole du gène: SLC6A7
• Identification du gène (NCBI): 6534
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC6A7 also known as PROT, belongs to the solute Carrier 6 gene family. SLC6A7 is a high-affinity mammalian brain L-proline transporter, which is different from other sodium-dependent plasma membrane carriers, and has unique pharmacological specificity, kinetic properties, and ionic requirements. SLC6A7 is a brain specific sodium (and chloride)-dependent proline transporter, that terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals(PMID: 7651355).

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