Anticorps Polyclonal de lapin anti-SLC6A8

• Phare
• Validé par KD/KO

SLC6A8 Polyclonal Antibody for WB, IHC, IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20299-1-PBS

Synonymes

Sodium- and chloride-dependent creatine transporter 1, CT1, CRTR, CRT, Creatine transporter 1

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Galerie de données de validation

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  WB analysis using 20299-1-AP (same clone as 20299-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20299-1-AP (SLC6A8 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

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  WB analysis of HUVEC using 20299-1-AP (same clone as 20299-1-PBS)

  HUVEC cells were subjected to SDS PAGE followed by western blot with 20299-1-AP (SLC6A8 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20299-1-AP (SLC6A8 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20299-1-AP (SLC6A8 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20299-1-AP (SLC6A8 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 20299-1-AP (SLC6A8 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

• 

  IF Staining of mouse brain using 20299-1-AP (same clone as 20299-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using 20299-1-AP (SLC6A8 antibody) at dilution of 1:50 and CoraLite488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 20299-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20299-1-PBS cible SLC6A8 dans les applications de WB, IHC, IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC6A8 Protéine recombinante Ag14110
• Nom complet: solute carrier family 6 (neurotransmitter transporter, creatine), member 8
• Masse moléculaire calculée: 635 aa, 71 kDa
• Poids moléculaire observé: 65-70 kDa
• Numéro d’acquisition GenBank: BC012355
• Symbole du gène: SLC6A8
• Identification du gène (NCBI): 6535
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC6A8, also known as the sodium- and chloride-dependent creatine transporter 1 (CT1), plays a critical role in transporting creatine, a crucial molecule for energy metabolism, into cells. SLC6A8 belongs to the solute carrier family 6 (SLC6), responsible for transporting diverse molecules across cell membranes. SLC6A8 expression is highest in muscle, kidney, and other tissues with high energy demands. Mutations in SLC6A8 cause creatine transporter deficiency, an X-linked mental retardation disorder (PMID: 17465020).

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