Anticorps Polyclonal de lapin anti-SLC7A2

SLC7A2 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 30232-1-PBS

Synonymes

HCAT2, Cationic amino acid transporter 2, CAT-2

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Galerie de données de validation

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  WB analysis using 30232-1-AP (same clone as 30232-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 30232-1-AP (SLC7A2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30232-1-PBS in a different storage buffer formulation.

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  IHC staining of human stomach cancer using 30232-1-AP (same clone as 30232-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human stomach cancer tissue slide using 30232-1-AP (SLC7A2 antibody) at dilution of 1:160 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 30232-1-PBS in a different storage buffer formulation.

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Informations sur le produit

30232-1-PBS cible SLC7A2 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: SLC7A2 Protéine recombinante Ag31207
• Nom complet: solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
• Masse moléculaire calculée: 698 aa, 76 kDa
• Poids moléculaire observé: 76 kDa
• Numéro d’acquisition GenBank: BC104905
• Symbole du gène: SLC7A2
• Identification du gène (NCBI): 6542
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Solute carrier family 7 member 2 (SLC7A2), also known as CAT2, is a member of the solute carrier superfamily. It functions as a cationic amino acid transporter, which can transport cationic amino acids (arginine, lysine and ornithine) into the cytosol and regulate inflammation (PMID: 35152203). It has been shown that lower SLC7A2 expression is associated with worse prognosis of ovarian cancer and hepatocellular carcinoma (PMID: 34108444; 32647070), and SLC7A2 deficiency in inflammatory bowel tissues increases the risk of inflammation-associated colon tumorigenesis (PMID: 30202097)

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